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Autophagy in the heart is enhanced and independent of disease progression in mus musculus dystrophinopathy models

BACKGROUND: Duchenne muscular dystrophy is a muscle wasting disease caused by dystrophin gene mutations resulting in dysfunctional dystrophin protein. Autophagy, a proteolytic process, is impaired in dystrophic skeletal muscle though little is known about the effect of dystrophin deficiency on autop...

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Detalles Bibliográficos
Autores principales: Spaulding, HR, Ballmann, C, Quindry, JC, Hudson, MB, Selsby, JT
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6790947/
https://www.ncbi.nlm.nih.gov/pubmed/31656622
http://dx.doi.org/10.1177/2048004019879581