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Soluble egg antigen of Schistosoma japonicum induces pyroptosis in hepatic stellate cells by modulating ROS production

BACKGROUND: Inflammation-induced dysfunction of hepatic stellate cells (HSCs) is involved in schistosomiasis-associated liver fibrosis, and soluble egg antigen (SEA) is a crucial pathogen-associated molecular pattern associated with liver injury in schistosomiasis. In addition, numerous studies have...

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Detalles Bibliográficos
Autores principales: Kong, De-Long, Kong, Fan-Yun, Liu, Xiang-Ye, Yan, Chao, Cui, Jie, Tang, Ren-Xian, Zheng, Kui-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791022/
https://www.ncbi.nlm.nih.gov/pubmed/31610797
http://dx.doi.org/10.1186/s13071-019-3729-8