High Effectiveness in Actions of Carfilzomib on Delayed-Rectifier K(+) Current and on Spontaneous Action Potentials

Carfilzomib (CFZ, Kyprolis(®)) is widely recognized as an irreversible inhibitor of proteasome activity; however, its actions on ion currents in electrically excitable cells are largely unresolved. The possible actions of CFZ on ionic currents and membrane potential in pituitary GH(3), A7r5 vascular...

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Detalles Bibliográficos
Autores principales: So, Edmund Cheung, Liu, Ping-Yen, Lee, Chien-Ching, Wu, Sheng-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791059/
https://www.ncbi.nlm.nih.gov/pubmed/31649537
http://dx.doi.org/10.3389/fphar.2019.01163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791059/
https://www.ncbi.nlm.nih.gov/pubmed/31649537
http://dx.doi.org/10.3389/fphar.2019.01163

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