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Indirect Tumor Inhibitory Effects of MicroRNA-124 through Targeting EZH2 in The Multiple Myeloma Cell Line

OBJECTIVE: Multiple myeloma (MM) is an incurable plasma cell malignancy. Several genetic and epigenetic changes affect numerous critical genes expression status in this disorder. CDKN2A gene is expressed at low level in almost all cases with MM disease. The mechanism of this gene down-regulation has...

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Detalles Bibliográficos
Autores principales: Sabour Takanlu, Javid, Aghaie Fard, Arad, Mohammdi, Saeed, Hosseini Rad, Seyed Mohammad Ali, Abroun, Saeid, Nikbakht, Mohsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791060/
https://www.ncbi.nlm.nih.gov/pubmed/31606963
http://dx.doi.org/10.22074/cellj.2020.6492