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Drugs and Clinical Approaches Targeting the Antiapoptotic Protein: A Review

B-cell lymphoma 2 (Bcl-2) is a regulator protein involved in apoptosis. In the past few decades, this protein has been demonstrated to have high efficacy in cancer therapy, and several approaches targeting Bcl-2 have been tested clinically (e.g., oblimersen, ABT-737, ABT-263, obatoclax mesylate, and...

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Detalles Bibliográficos
Autores principales: Han, Zeping, Liang, Jiening, Li, Yuguang, He, Jinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791192/
https://www.ncbi.nlm.nih.gov/pubmed/31662966
http://dx.doi.org/10.1155/2019/1212369