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Toward the Optimization of (+)-[(11)C]PHNO Synthesis: Time Reduction and Process Validation

(+)-[(11)C]PHNO, a dopamine D(2/3) receptor agonistic radiotracer, is applied for investigating the dopaminergic system via positron emission tomography (PET). An improved understanding of neuropsychiatric disorders associated with dysfunctions in the dopamine system and the underlying mechanism is...

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Detalles Bibliográficos
Autores principales: Pfaff, Sarah, Philippe, Cécile, Nics, Lukas, Berroterán-Infante, Neydher, Pallitsch, Katharina, Rami-Mark, Christina, Weidenauer, Ana, Sauerzopf, Ulrich, Willeit, Matthäus, Mitterhauser, Markus, Hacker, Marcus, Wadsak, Wolfgang, Pichler, Verena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791232/
https://www.ncbi.nlm.nih.gov/pubmed/31656452
http://dx.doi.org/10.1155/2019/4292596