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Vascular Endothelial Growth Factor Is Regulated by the Canonical and Noncanonical Transforming Growth Factor-β Pathway in Synovial Fibroblasts Derived from Osteoarthritis Patients

BACKGROUND: Previous studies suggest the presence of an association of vascular endothelial growth factor (VEGF) with osteoarthritis (OA) severity and pain in patients with knee OA. VEGF expression in human synovial fibroblasts (SFs) is induced by transforming growth factor-beta (TGFβ). However, the...

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Detalles Bibliográficos
Autores principales: Takano, Shotaro, Uchida, Kentaro, Shoji, Shintaro, Itakura, Makoto, Iwase, Dai, Aikawa, Jun, Mukai, Manabu, Sekiguchi, Hiroyuki, Inoue, Gen, Takaso, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791277/
https://www.ncbi.nlm.nih.gov/pubmed/31662989
http://dx.doi.org/10.1155/2019/6959056