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Vascular Endothelial Growth Factor Is Regulated by the Canonical and Noncanonical Transforming Growth Factor-β Pathway in Synovial Fibroblasts Derived from Osteoarthritis Patients
BACKGROUND: Previous studies suggest the presence of an association of vascular endothelial growth factor (VEGF) with osteoarthritis (OA) severity and pain in patients with knee OA. VEGF expression in human synovial fibroblasts (SFs) is induced by transforming growth factor-beta (TGFβ). However, the...
Autores principales: | Takano, Shotaro, Uchida, Kentaro, Shoji, Shintaro, Itakura, Makoto, Iwase, Dai, Aikawa, Jun, Mukai, Manabu, Sekiguchi, Hiroyuki, Inoue, Gen, Takaso, Masashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791277/ https://www.ncbi.nlm.nih.gov/pubmed/31662989 http://dx.doi.org/10.1155/2019/6959056 |
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