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A Unique Case Report on Methadone Used for Treatment of Opioid-induced Hyperalgesia in a Cancer Patient at the End of Life

Opioids are the cornerstone of palliative pain management. Opioids work on the mu-opioid receptor as an agonist for the treatment of pain. Repeated exposure to opioids over time can lead to undesired desensitization of the antinociceptive receptor while sensitizing the N-methyl-D-aspartate (NMDA) pa...

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Detalles Bibliográficos
Autores principales: Bitar, Heather N, Cipta, Andre M, Lee, Kuo-Wei, Woo, Wesley S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791394/
https://www.ncbi.nlm.nih.gov/pubmed/31620320
http://dx.doi.org/10.7759/cureus.5394