Evaluating Chemicals for Thyroid Disruption: Opportunities and Challenges with in Vitro Testing and Adverse Outcome Pathway Approaches

BACKGROUND: Extensive clinical and experimental research documents the potential for chemical disruption of thyroid hormone (TH) signaling through multiple molecular targets. Perturbation of TH signaling can lead to abnormal brain development, cognitive impairments, and other adverse outcomes in hum...

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Detalles Bibliográficos
Autores principales: Noyes, Pamela D., Friedman, Katie Paul, Browne, Patience, Haselman, Jonathan T., Gilbert, Mary E., Hornung, Michael W., Barone, Stan, Crofton, Kevin M., Laws, Susan C., Stoker, Tammy E., Simmons, Steven O., Tietge, Joseph E., Degitz, Sigmund J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2019
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791490/
https://www.ncbi.nlm.nih.gov/pubmed/31487205
http://dx.doi.org/10.1289/EHP5297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791490/
https://www.ncbi.nlm.nih.gov/pubmed/31487205
http://dx.doi.org/10.1289/EHP5297

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