A scale-free analysis of the HIV-1 genome demonstrates multiple conserved regions of structural and functional importance

HIV-1 replicates via a low-fidelity polymerase with a high mutation rate; strong conservation of individual nucleotides is highly indicative of the presence of critical structural or functional properties. Identifying such conservation can reveal novel insights into viral behaviour. We analysed 3651...

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Detalles Bibliográficos
Autores principales: Skittrall, Jordan P., Ingemarsdotter, Carin K., Gog, Julia R., Lever, Andrew M. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791557/
https://www.ncbi.nlm.nih.gov/pubmed/31545786
http://dx.doi.org/10.1371/journal.pcbi.1007345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791557/
https://www.ncbi.nlm.nih.gov/pubmed/31545786
http://dx.doi.org/10.1371/journal.pcbi.1007345

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