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Alpha-1 Antitrypsin Attenuates Acute Lung Allograft Injury in a Rat Lung Transplant Model

Ischemia-reperfusion injury (IRI) after lung transplantation triggers a cascade of inflammatory changes that can contribute to acute allograft injury. This influences both the short- and long-term survival of the lung allograft. Alpha-1 antitrypsin (AAT) is a protease inhibitor with known anti-infla...

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Detalles Bibliográficos
Autores principales: Emtiazjoo, Amir M., Hu, Hanbo, Lu, Li, Brantly, Mark L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791593/
https://www.ncbi.nlm.nih.gov/pubmed/31723592
http://dx.doi.org/10.1097/TXD.0000000000000898