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1-Palmitoyl-2-Linoleoyl-3-Acetyl-rac-Glycerol Attenuates Streptozotocin-Induced Pancreatic Beta Cell Damage by Promoting Glucose Transporter 2 Endocytosis

Streptozotocin (STZ) is widely used to induce diabetic rodent models. It is specifically toxic to pancreatic beta cells and causes severe destruction and dysfunction. We investigated the effect of 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) on an STZ-induced diabetic mouse model. PLAG atten...

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Detalles Bibliográficos
Autores principales: Kim, Jimin, Kim, Joo Heon, Sohn, Ki-Young, Yoon, Sun Young, Kim, Jae Wha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791655/
https://www.ncbi.nlm.nih.gov/pubmed/31481450
http://dx.doi.org/10.1128/MCB.00157-19