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DNA hypermethylation in disease: mechanisms and clinical relevance
Increasing numbers of studies implicate abnormal DNA methylation in cancer and many non-malignant diseases. This is consistent with numerous findings about differentiation-associated changes in DNA methylation at promoters, enhancers, gene bodies, and sites that control higher-order chromatin struct...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Taylor & Francis
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791695/ https://www.ncbi.nlm.nih.gov/pubmed/31284823 http://dx.doi.org/10.1080/15592294.2019.1638701 |