Cargando…
DNA hypermethylation in disease: mechanisms and clinical relevance
Increasing numbers of studies implicate abnormal DNA methylation in cancer and many non-malignant diseases. This is consistent with numerous findings about differentiation-associated changes in DNA methylation at promoters, enhancers, gene bodies, and sites that control higher-order chromatin struct...
Autor principal: | Ehrlich, Melanie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791695/ https://www.ncbi.nlm.nih.gov/pubmed/31284823 http://dx.doi.org/10.1080/15592294.2019.1638701 |
Ejemplares similares
-
Developmentally linked human DNA hypermethylation is associated with down-modulation, repression, and upregulation of transcription
por: Baribault, Carl, et al.
Publicado: (2018) -
Promoter-Adjacent DNA Hypermethylation Can Downmodulate Gene Expression: TBX15 in the Muscle Lineage
por: Ehrlich, Kenneth C., et al.
Publicado: (2022) -
DNA Hypermethylation and Unstable Repeat Diseases: A Paradigm of Transcriptional Silencing to Decipher the Basis of Pathogenic Mechanisms
por: Poeta, Loredana, et al.
Publicado: (2020) -
Endometrial Cancer and Hypermethylation: Regulation of DNA and MicroRNA by Epigenetics
por: Banno, Kouji, et al.
Publicado: (2012) -
Prognostic Relevance of Promoter Hypermethylation of Multiple Genes in Breast Cancer Patients
por: Sharma, Gayatri, et al.
Publicado: (2009)