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DNA hypermethylation in disease: mechanisms and clinical relevance

Increasing numbers of studies implicate abnormal DNA methylation in cancer and many non-malignant diseases. This is consistent with numerous findings about differentiation-associated changes in DNA methylation at promoters, enhancers, gene bodies, and sites that control higher-order chromatin struct...

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Detalles Bibliográficos
Autor principal: Ehrlich, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791695/
https://www.ncbi.nlm.nih.gov/pubmed/31284823
http://dx.doi.org/10.1080/15592294.2019.1638701

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