Silencing of Glutathione S-Transferase Pi Inhibits Cancer Cell Growth via Oxidative Stress Induced by Mitochondria Dysfunction

Antitumor drug development based on the concept of intervening in the antioxidant system of cancer cells has been gaining increased interest. In this study, we propose a promising strategy for cancer treatment using modulation of oxidative stress by suppression of glutathione S-transferases (GSTs),...

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Detalles Bibliográficos
Autores principales: Fujitani, Naoki, Yoneda, Akihiro, Takahashi, Motoko, Takasawa, Akira, Aoyama, Tomoyuki, Miyazaki, Tadaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791853/
https://www.ncbi.nlm.nih.gov/pubmed/31611630
http://dx.doi.org/10.1038/s41598-019-51462-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791853/
https://www.ncbi.nlm.nih.gov/pubmed/31611630
http://dx.doi.org/10.1038/s41598-019-51462-9

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