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Silencing of Glutathione S-Transferase Pi Inhibits Cancer Cell Growth via Oxidative Stress Induced by Mitochondria Dysfunction
Antitumor drug development based on the concept of intervening in the antioxidant system of cancer cells has been gaining increased interest. In this study, we propose a promising strategy for cancer treatment using modulation of oxidative stress by suppression of glutathione S-transferases (GSTs),...
Autores principales: | Fujitani, Naoki, Yoneda, Akihiro, Takahashi, Motoko, Takasawa, Akira, Aoyama, Tomoyuki, Miyazaki, Tadaaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791853/ https://www.ncbi.nlm.nih.gov/pubmed/31611630 http://dx.doi.org/10.1038/s41598-019-51462-9 |
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