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CCL2 promotes macrophages-associated chemoresistance via MCPIP1 dual catalytic activities in multiple myeloma

We previously showed that the chemokine CCL2 can recruit macrophages (Mφs) to the bone marrow (BM) in multiple myeloma (MM) and that myeloma-associated Mφs are important in drug resistance. Here, we explore the role of increased CCL2 expression in the BM microenvironment of MM and elucidate the unde...

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Detalles Bibliográficos
Autores principales: Xu, Ruyi, Li, Yi, Yan, Haimeng, Zhang, Enfan, Huang, Xi, Chen, Qingxiao, Chen, Jing, Qu, Jianwei, Liu, Yang, He, Jingsong, Yi, Qing, Cai, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791869/
https://www.ncbi.nlm.nih.gov/pubmed/31611552
http://dx.doi.org/10.1038/s41419-019-2012-4