Switch of the interactions between the ribosomal stalk and EF1A in the GTP- and GDP-bound conformations

Translation elongation factor EF1A delivers aminoacyl-tRNA to the ribosome in a GTP-bound form, and is released from the ribosome in a GDP-bound form. This association/dissociation cycle proceeds efficiently via a marked conformational change in EF1A. EF1A function is dependent on the ribosomal “sta...

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Detalles Bibliográficos
Autores principales: Maruyama, Kei, Imai, Hirotatsu, Kawamura, Momoko, Ishino, Sonoko, Ishino, Yoshizumi, Ito, Kosuke, Uchiumi, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791870/
https://www.ncbi.nlm.nih.gov/pubmed/31611569
http://dx.doi.org/10.1038/s41598-019-51266-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791870/
https://www.ncbi.nlm.nih.gov/pubmed/31611569
http://dx.doi.org/10.1038/s41598-019-51266-x

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