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Switch of the interactions between the ribosomal stalk and EF1A in the GTP- and GDP-bound conformations
Translation elongation factor EF1A delivers aminoacyl-tRNA to the ribosome in a GTP-bound form, and is released from the ribosome in a GDP-bound form. This association/dissociation cycle proceeds efficiently via a marked conformational change in EF1A. EF1A function is dependent on the ribosomal “sta...
Autores principales: | Maruyama, Kei, Imai, Hirotatsu, Kawamura, Momoko, Ishino, Sonoko, Ishino, Yoshizumi, Ito, Kosuke, Uchiumi, Toshio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791870/ https://www.ncbi.nlm.nih.gov/pubmed/31611569 http://dx.doi.org/10.1038/s41598-019-51266-x |
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