A docking-based structural analysis of geldanamycin-derived inhibitor binding to human or Leishmania Hsp90

Leishmaniasis is a neglected disease that affects millions of individuals around the world. Regardless of clinical form, treatment is based primarily on the use of pentavalent antimonials. However, such treatments are prolonged and present intense side effects, which lead to patient abandonment in m...

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Detalles Bibliográficos
Autores principales: Palma, Luana Carneiro, Ferreira, Luiz Felipe Gomes Rebello, Petersen, Antonio Luis de Oliveira Almeida, Dias, Beatriz Rocha Simões, Menezes, Juliana Perrone Bezerra de, Moreira, Diogo Rodrigo de Magalhães, Hernandes, Marcelo Zaldini, Veras, Patricia Sampaio Tavares
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791876/
https://www.ncbi.nlm.nih.gov/pubmed/31611575
http://dx.doi.org/10.1038/s41598-019-51239-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791876/
https://www.ncbi.nlm.nih.gov/pubmed/31611575
http://dx.doi.org/10.1038/s41598-019-51239-0

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