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A docking-based structural analysis of geldanamycin-derived inhibitor binding to human or Leishmania Hsp90
Leishmaniasis is a neglected disease that affects millions of individuals around the world. Regardless of clinical form, treatment is based primarily on the use of pentavalent antimonials. However, such treatments are prolonged and present intense side effects, which lead to patient abandonment in m...
Autores principales: | Palma, Luana Carneiro, Ferreira, Luiz Felipe Gomes Rebello, Petersen, Antonio Luis de Oliveira Almeida, Dias, Beatriz Rocha Simões, Menezes, Juliana Perrone Bezerra de, Moreira, Diogo Rodrigo de Magalhães, Hernandes, Marcelo Zaldini, Veras, Patricia Sampaio Tavares |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791876/ https://www.ncbi.nlm.nih.gov/pubmed/31611575 http://dx.doi.org/10.1038/s41598-019-51239-0 |
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