Gpr17 deficiency in POMC neurons ameliorates the metabolic derangements caused by long-term high-fat diet feeding

BACKGROUND: Proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (ARH) control energy homeostasis by sensing hormonal and nutrient cues and activating secondary melanocortin sensing neurons. We identified the expression of a G protein-coupled receptor, Gpr17, in the ARH and...

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Detalles Bibliográficos
Autores principales: Reilly, Austin M., Zhou, Shudi, Panigrahi, Sunil K., Yan, Shijun, Conley, Jason M., Sheets, Patrick L., Wardlaw, Sharon L., Ren, Hongxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791877/
https://www.ncbi.nlm.nih.gov/pubmed/31611548
http://dx.doi.org/10.1038/s41387-019-0096-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791877/
https://www.ncbi.nlm.nih.gov/pubmed/31611548
http://dx.doi.org/10.1038/s41387-019-0096-7

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