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Cannabidiol directly targets mitochondria and disturbs calcium homeostasis in acute lymphoblastic leukemia

Anticancer properties of non-psychoactive cannabinoid cannabidiol (CBD) have been demonstrated on tumors of different histogenesis. Different molecular targets for CBD were proposed, including cannabinoid receptors and some plasma membrane ion channels. Here we have shown that cell lines derived fro...

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Detalles Bibliográficos
Autores principales: Olivas-Aguirre, Miguel, Torres-López, Liliana, Valle-Reyes, Juan Salvador, Hernández-Cruz, Arturo, Pottosin, Igor, Dobrovinskaya, Oxana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791884/
https://www.ncbi.nlm.nih.gov/pubmed/31611561
http://dx.doi.org/10.1038/s41419-019-2024-0