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First-in-human, Randomized, Double-blind Clinical Trial of Differentially Adjuvanted PAMVAC, A Vaccine Candidate to Prevent Pregnancy-associated Malaria

BACKGROUND: Malaria in pregnancy has major impacts on mother and child health. To complement existing interventions, such as intermittent preventive treatment and use of impregnated bed nets, we developed a malaria vaccine candidate with the aim of reducing sequestration of asexual “blood-stage” par...

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Detalles Bibliográficos
Autores principales: Mordmüller, Benjamin, Sulyok, Mihály, Egger-Adam, Diane, Resende, Mafalda, de Jongh, Willem A, Jensen, Mette H, Smedegaard, Helle Holm, Ditlev, Sisse B, Soegaard, Max, Poulsen, Lars, Dyring, Charlotte, Calle, Carlos Lamsfus, Knoblich, Annette, Ibáñez, Javier, Esen, Meral, Deloron, Philippe, Ndam, Nicaise, Issifou, Saadou, Houard, Sophie, Howard, Randall F, Reed, Steven G, Leroy, Odile, Luty, Adrian J F, Theander, Thor G, Kremsner, Peter G, Salanti, Ali, Nielsen, Morten A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792113/
https://www.ncbi.nlm.nih.gov/pubmed/30629148
http://dx.doi.org/10.1093/cid/ciy1140