Transcriptional activation of CBFβ by CDK11(p110) is necessary to promote osteosarcoma cell proliferation

BACKGROUND: Aberrant expression of cyclin-dependent protein kinases (CDK) is a hallmark of cancer. CDK11 plays a crucial role in cancer cell growth and proliferation. However, the molecular mechanisms of CDK11 and CDK11 transcriptionally regulated genes are largely unknown. METHODS: In this study, w...

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Detalles Bibliográficos
Autores principales: Feng, Yong, Liao, Yunfei, Zhang, Jianming, Shen, Jacson, Shao, Zengwu, Hornicek, Francis, Duan, Zhenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792216/
https://www.ncbi.nlm.nih.gov/pubmed/31610798
http://dx.doi.org/10.1186/s12964-019-0440-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792216/
https://www.ncbi.nlm.nih.gov/pubmed/31610798
http://dx.doi.org/10.1186/s12964-019-0440-5

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