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Transcriptional activation of CBFβ by CDK11(p110) is necessary to promote osteosarcoma cell proliferation
BACKGROUND: Aberrant expression of cyclin-dependent protein kinases (CDK) is a hallmark of cancer. CDK11 plays a crucial role in cancer cell growth and proliferation. However, the molecular mechanisms of CDK11 and CDK11 transcriptionally regulated genes are largely unknown. METHODS: In this study, w...
Autores principales: | Feng, Yong, Liao, Yunfei, Zhang, Jianming, Shen, Jacson, Shao, Zengwu, Hornicek, Francis, Duan, Zhenfeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792216/ https://www.ncbi.nlm.nih.gov/pubmed/31610798 http://dx.doi.org/10.1186/s12964-019-0440-5 |
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