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Sox2 promotes expression of the ST6Gal-I glycosyltransferase in ovarian cancer cells

BACKGROUND: The ST6Gal-I glycosyltransferase, which adds α2–6-linked sialic acids to N-glycosylated proteins is upregulated in a wide range of malignancies including ovarian cancer. Prior studies have shown that ST6Gal-I-mediated sialylation of select surface receptors remodels intracellular signali...

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Detalles Bibliográficos
Autores principales: Dorsett, Kaitlyn A., Jones, Robert B., Ankenbauer, Katherine E., Hjelmeland, Anita B., Bellis, Susan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792265/
https://www.ncbi.nlm.nih.gov/pubmed/31610800
http://dx.doi.org/10.1186/s13048-019-0574-5