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Use of a Mouse Model and Human Umbilical Vein Endothelial Cells to Investigate the Effect of Arsenic Exposure on Vascular Endothelial Function and the Associated Role of Calpains

BACKGROUND: Arsenic (As) is a well-known environmental contaminant. Chronic exposure to As is known to increase the risk of cardiovascular diseases, including atherosclerosis, hypertension, diabetes, and stroke. However, the detailed mechanisms by which As causes vascular dysfunction involving endot...

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Detalles Bibliográficos
Autores principales: Cai, Zhihui, Zhang, Yanqing, Zhang, Yutian, Miao, Xiaofeng, Li, Shu, Yang, Hui, Ling, Qinjie, Hoffmann, Peter R., Huang, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792366/
https://www.ncbi.nlm.nih.gov/pubmed/31274337
http://dx.doi.org/10.1289/EHP4538