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Combination of Selected MET and EGFR Inhibitors Decreases Melanoma Cells’ Invasive Abilities

We have previously shown that combination of foretinib, an inhibitor of MET (hepatocyte growth factor receptor), with gefitinib or lapatinib, inhibitors of EGFR (epidermal growth factor receptor), has a synergistic cytotoxic effect on melanoma cells. However, there are cancer cells resistant to drug...

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Detalles Bibliográficos
Autores principales: Simiczyjew, Aleksandra, Pietraszek-Gremplewicz, Katarzyna, Dratkiewicz, Ewelina, Podgórska, Marta, Matkowski, Rafał, Ziętek, Marcin, Nowak, Dorota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792435/
https://www.ncbi.nlm.nih.gov/pubmed/31649529
http://dx.doi.org/10.3389/fphar.2019.01116