Hexokinase 2 dimerization and interaction with voltage‐dependent anion channel promoted resistance to cell apoptosis induced by gemcitabine in pancreatic cancer

Gemcitabine (GEM) is the standard chemotherapy drug for pancreatic cancer. Because of widespread drug resistance, the effect is limited. Therefore, it is urgent to reveal the underlying mechanism. Glycolysis is the most remarkable character of tumor aberrant metabolism, which plays vital roles on tu...

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Detalles Bibliográficos
Autores principales: Fan, Kun, Fan, Zhiyao, Cheng, He, Huang, Qiuyi, Yang, Chao, Jin, Kaizhou, Luo, Guopei, Yu, Xianjun, Liu, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Clinical Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792491/
https://www.ncbi.nlm.nih.gov/pubmed/31426130
http://dx.doi.org/10.1002/cam4.2463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792491/
https://www.ncbi.nlm.nih.gov/pubmed/31426130
http://dx.doi.org/10.1002/cam4.2463

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