The Nuclear Export Inhibitor Selinexor Inhibits Hypoxia Signaling Pathways And 3D Spheroid Growth Of Cancer Cells

PURPOSE: The nucleocytoplasmic transport of macromolecules is critical for both cell physiology and pathophysiology. Exportin 1 (XPO1), the major nuclear export receptor, is involved in the cellular adaptation to reduced oxygen availability by controlling the nuclear activity of the hypoxia-inducibl...

Descripción completa

Detalles Bibliográficos
Autores principales: Depping, Reinhard, von Fallois, Moritz, Landesman, Yosef, Kosyna, Friederike Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6793465/
https://www.ncbi.nlm.nih.gov/pubmed/31632086
http://dx.doi.org/10.2147/OTT.S213208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6793465/
https://www.ncbi.nlm.nih.gov/pubmed/31632086
http://dx.doi.org/10.2147/OTT.S213208

Ejemplares similares