Engineered oncolytic virus for the treatment of cholesteatoma: A pilot in vivo study

OBJECTIVE: Determine if oncolytic herpes simplex virus (oHSV) can eradicate cholesteatoma (CHST) in a gerbil model. METHODS: An in vivo model of CHST was developed in Mongolian gerbils by combining Pseudomonas aeruginosa inoculation with double ligation of the external auditory canal (EAC). CHST siz...

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Detalles Bibliográficos
Autores principales: Samy, Ravi N., Earl, Brian R., Lipschitz, Noga, Schweinzger, Ivy, Currier, Mark, Cripe, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Otology, Neurotology, and Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6793611/
https://www.ncbi.nlm.nih.gov/pubmed/31637298
http://dx.doi.org/10.1002/lio2.307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6793611/
https://www.ncbi.nlm.nih.gov/pubmed/31637298
http://dx.doi.org/10.1002/lio2.307

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