Celecoxib enhances the sensitivity of non-small-cell lung cancer cells to radiation-induced apoptosis through downregulation of the Akt/mTOR signaling pathway and COX-2 expression

The current study aimed to identify the radiosensitizing effect of celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, in combination with radiotherapy in non-small-cell lung cancer (NSCLC) cells. The combination of celecoxib potentiated radiation-induced apoptosis; however, no changes in cel...

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Detalles Bibliográficos
Autores principales: Zhang, Pan, He, Dan, Song, Erqun, Jiang, Mingdong, Song, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6793859/
https://www.ncbi.nlm.nih.gov/pubmed/31613929
http://dx.doi.org/10.1371/journal.pone.0223760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6793859/
https://www.ncbi.nlm.nih.gov/pubmed/31613929
http://dx.doi.org/10.1371/journal.pone.0223760

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