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The Ps and Qs of alarmone synthesis in Staphylococcus aureus

During the stringent response, bacteria synthesize guanosine-3’,5’-bis(diphosphate) (ppGpp) and guanosine-5’-triphosphate 3’-diphosphate (pppGpp), which act as secondary messengers to promote cellular survival and adaptation. (p)ppGpp ‘alarmones’ are synthesized and/or hydrolyzed by proteins belongi...

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Detalles Bibliográficos
Autores principales: Yang, Ning, Xie, Shujie, Tang, Nga-Yeung, Choi, Mei Yee, Wang, Ying, Watt, Rory M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6793942/
https://www.ncbi.nlm.nih.gov/pubmed/31613897
http://dx.doi.org/10.1371/journal.pone.0213630