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Exosomes and STUB1/CHIP cooperate to maintain intracellular proteostasis
Deregulation of proteostasis is a main feature of many age-related diseases, often leading to the accumulation of toxic oligomers and insoluble protein aggregates that accumulate intracellularly or in the extracellular space. To understand the mechanisms whereby toxic or otherwise unwanted proteins...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794069/ https://www.ncbi.nlm.nih.gov/pubmed/31613922 http://dx.doi.org/10.1371/journal.pone.0223790 |