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Exosomes and STUB1/CHIP cooperate to maintain intracellular proteostasis

Deregulation of proteostasis is a main feature of many age-related diseases, often leading to the accumulation of toxic oligomers and insoluble protein aggregates that accumulate intracellularly or in the extracellular space. To understand the mechanisms whereby toxic or otherwise unwanted proteins...

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Detalles Bibliográficos
Autores principales: Ferreira, Joao Vasco, Rosa Soares, Ana, Ramalho, José S., Ribeiro-Rodrigues, Teresa, Máximo, Catarina, Zuzarte, Mónica, Girão, Henrique, Pereira, Paulo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794069/
https://www.ncbi.nlm.nih.gov/pubmed/31613922
http://dx.doi.org/10.1371/journal.pone.0223790

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