Dissection of central clock function in Drosophila through cell-specific CRISPR-mediated clock gene disruption

In Drosophila, ~150 neurons expressing molecular clock proteins regulate circadian behavior. Sixteen of these neurons secrete the neuropeptide Pdf and have been called ‘master pacemakers’ because they are essential for circadian rhythms. A subset of Pdf(+) neurons (the morning oscillator) regulates...

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Detalles Bibliográficos
Autores principales: Delventhal, Rebecca, O'Connor, Reed M, Pantalia, Meghan M, Ulgherait, Matthew, Kim, Han X, Basturk, Maylis K, Canman, Julie C, Shirasu-Hiza, Mimi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794090/
https://www.ncbi.nlm.nih.gov/pubmed/31613218
http://dx.doi.org/10.7554/eLife.48308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794090/
https://www.ncbi.nlm.nih.gov/pubmed/31613218
http://dx.doi.org/10.7554/eLife.48308

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