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Dissection of central clock function in Drosophila through cell-specific CRISPR-mediated clock gene disruption
In Drosophila, ~150 neurons expressing molecular clock proteins regulate circadian behavior. Sixteen of these neurons secrete the neuropeptide Pdf and have been called ‘master pacemakers’ because they are essential for circadian rhythms. A subset of Pdf(+) neurons (the morning oscillator) regulates...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794090/ https://www.ncbi.nlm.nih.gov/pubmed/31613218 http://dx.doi.org/10.7554/eLife.48308 |