Genomewide Analysis of Mode of Action of the S-Adenosylmethionine Analogue Sinefungin in Leishmania infantum

To further our understanding of one-carbon metabolism in the protozoan parasite Leishmania, we conducted genomic screens to study how the parasite responded to sinefungin (SNF) selection. SNF is a structural analogue of S-adenosylmethionine (AdoMet), a key methyl group donor to a number of biomolecu...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Arijit, Sharma, Mansi, Pakkinathan, Charles, Rosen, Barry P., Leprohon, Philippe, Ouellette, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794121/
https://www.ncbi.nlm.nih.gov/pubmed/31615876
http://dx.doi.org/10.1128/mSystems.00416-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794121/
https://www.ncbi.nlm.nih.gov/pubmed/31615876
http://dx.doi.org/10.1128/mSystems.00416-19

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