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Role of NS5A-L31/Y93 Double Wild-type in Failure of Glecaprevir/Pibrentasvir Double Therapy in Two Patients with a History of Direct-acting Antiviral Agent Failure: An Ultra-deep Sequencing Analysis

We experienced two cases of hepatitis C virus (HCV) eradication failure in patients with a history of non-responsiveness to previous treatments with direct-acting antiviral agents (DAAs) who were subsequently treated with the combination of glecaprevir and pibrentasvir (GLE/PIB). Direct sequencing a...

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Detalles Bibliográficos
Autores principales: Sano, Tomoya, Akuta, Norio, Suzuki, Fumitaka, Kasuya, Kayoko, Fujiyama, Shunichiro, Kawamura, Yusuke, Sezaki, Hitomi, Hosaka, Tetsuya, Saitoh, Satoshi, Kobayashi, Masahiro, Suzuki, Yoshiyuki, Kobayashi, Mariko, Arase, Yasuji, Ikeda, Kenji, Kumada, Hiromitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794189/
https://www.ncbi.nlm.nih.gov/pubmed/31178495
http://dx.doi.org/10.2169/internalmedicine.2604-18