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Glutathione deficiency induces epigenetic alterations of vitamin D metabolism genes in the livers of high-fat diet-fed obese mice

Obesity has been correlating with low levels of glutathione (GSH) and 25-hydroxyvitamin D3 (25(OH)VD(3)). The liver is the principal site for the 25(OH)VD(3) biosynthesis. This study investigated whether GSH deficiency induces epigenetic alterations that impair Vitamin D (VD) metabolism genes in the...

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Detalles Bibliográficos
Autores principales: Parsanathan, Rajesh, Jain, Sushil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794254/
https://www.ncbi.nlm.nih.gov/pubmed/31616013
http://dx.doi.org/10.1038/s41598-019-51377-5