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Soluble guanylyl cyclase α1 subunit is a key mediator of proliferation, survival, and migration in ECC-1 and HeLa cell lines

Soluble guanylyl cyclase (sGC) is a heterodimeric enzyme constituted by two subunits, α1 and β1. Previously we have shown that 17β-estradiol (E2) exerts opposite effects on these subunits by increasing α1 and decreasing both β1 expression and enzymatic activity. To date, the physiological relevance...

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Detalles Bibliográficos
Autores principales: Ronchetti, Sonia A., Pino, María Teresa L., Cordeiro, Georgina, Bollani, Sabrina N., Ricci, Analía G., Duvilanski, Beatriz H., Cabilla, Jimena P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794259/
https://www.ncbi.nlm.nih.gov/pubmed/31616026
http://dx.doi.org/10.1038/s41598-019-51420-5