Embryonic mesothelial-derived hepatic lineage of quiescent and heterogenous scar-orchestrating cells defined but suppressed by WT1

Activated hepatic stellate cells (aHSCs) orchestrate scarring during liver injury, with putative quiescent precursor mesodermal derivation. Here we use lineage-tracing from development, through adult homoeostasis, to fibrosis, to define morphologically and transcriptionally discreet subpopulations o...

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Detalles Bibliográficos
Autores principales: Kendall, Timothy James, Duff, Catherine Mary, Boulter, Luke, Wilson, David H., Freyer, Elisabeth, Aitken, Stuart, Forbes, Stuart John, Iredale, John Peter, Hastie, Nicholas Dixon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794268/
https://www.ncbi.nlm.nih.gov/pubmed/31615982
http://dx.doi.org/10.1038/s41467-019-12701-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794268/
https://www.ncbi.nlm.nih.gov/pubmed/31615982
http://dx.doi.org/10.1038/s41467-019-12701-9

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