Cargando…

Embryonic mesothelial-derived hepatic lineage of quiescent and heterogenous scar-orchestrating cells defined but suppressed by WT1

Activated hepatic stellate cells (aHSCs) orchestrate scarring during liver injury, with putative quiescent precursor mesodermal derivation. Here we use lineage-tracing from development, through adult homoeostasis, to fibrosis, to define morphologically and transcriptionally discreet subpopulations o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kendall, Timothy James, Duff, Catherine Mary, Boulter, Luke, Wilson, David H., Freyer, Elisabeth, Aitken, Stuart, Forbes, Stuart John, Iredale, John Peter, Hastie, Nicholas Dixon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794268/ https://www.ncbi.nlm.nih.gov/pubmed/31615982 http://dx.doi.org/10.1038/s41467-019-12701-9

Ejemplares similares

Ovarian Cancer-Associated Mesothelial Cells: Transdifferentiation to Minions of Cancer and Orchestrate Developing Peritoneal Dissemination
por: Mogi, Kazumasa, et al.
Publicado: (2021)

WT1 Is Necessary for the Proliferation and Migration of Cells of Renin Lineage Following Kidney Podocyte Depletion
por: Kaverina, Natalya V., et al.
Publicado: (2017)

WT1 expression in breast cancer disrupts the epithelial/mesenchymal balance of tumour cells and correlates with the metabolic response to docetaxel
por: Artibani, Mara, et al.
Publicado: (2017)

Embryonic cells contribute directly to the quiescent stem cell population in the adult mouse mammary gland
por: Boras-Granic, Kata, et al.
Publicado: (2014)

Wt1, the mesothelium and the origins and heterogeneity of visceral fat progenitors
por: Chau, You-Ying, et al.
Publicado: (2015)

Inflammation as an orchestrator of cutaneous scar formation: a review of the literature
por: Wilgus, Traci A.
Publicado: (2020)

Integration of geoscience frameworks into digital pathology analysis permits quantification of microarchitectural relationships in histological landscapes
por: Kendall, Timothy J., et al.
Publicado: (2020)

Phase Stability of Dross Particles in Hot-Dip Zn-55wt%Al-1.6wt%Si Galvanizing Bath
por: Qu, Dongdong, et al.
Publicado: (2023)

Restoration of WT1/miR-769-5p axis by HDAC1 inhibition promotes MMT reversal in mesenchymal-like mesothelial cells
por: Bontempi, Giulio, et al.
Publicado: (2022)

Acute Multiple Organ Failure in Adult Mice Deleted for the Developmental Regulator Wt1
por: Chau, You-Ying, et al.
Publicado: (2011)

In Vitro Derivation of Quiescent Mouse Embryonic Stem Cells Based on Distinct Mitochondrial Activity
por: Khoa, Le Tran Phuc, et al.
Publicado: (2020)

Anaphylatoxins orchestrate Th17 response via interactions between CD16(+) monocytes and pleural mesothelial cells in tuberculous pleural effusion
por: Deng, Shuanglinzi, et al.
Publicado: (2021)

Lesion of Aggregated Monocytes and Mesothelial Cells: Mesothelial/Monocytic Incidental Cardiac Lesion
por: Erinanç, Hilal, et al.
Publicado: (2013)

WT1 expression in vessels varies with histopathological grade in tumour-bearing and control tissue from patients with breast cancer
por: McGregor, Richard J., et al.
Publicado: (2018)

Lineage tracing of Foxd1‐expressing embryonic progenitors to assess the role of divergent embryonic lineages on adult dermal fibroblast function
por: Walker, John T., et al.
Publicado: (2021)

Carbon Nanotubes and Other Engineered Nanoparticles Induced Pathophysiology on Mesothelial Cells and Mesothelial Membranes
por: Sinis, Sotirios I., et al.
Publicado: (2018)

SNW1 Orchestrates BMP Signaling in Early Embryonic Patterning
por: Sedwick, Caitlin
Publicado: (2011)

Combined Therapy Using Human Corneal Stromal Stem Cells and Quiescent Keratocytes to Prevent Corneal Scarring after Injury
por: Jhanji, Vishal, et al.
Publicado: (2022)

Editorial: Mesothelial Physiology and Pathophysiology
por: Zarogiannis, Sotirios G.
Publicado: (2018)

Polycomb Repressive Complex 2 Regulates Lineage Fidelity during Embryonic Stem Cell Differentiation
por: Thornton, Seraphim R., et al.
Publicado: (2014)

X-inactivation analysis of embryonic lethality in Ocrl(wt/−);Inpp5b(−/−) mice
por: Bernard, David J., et al.
Publicado: (2010)

Injury in aged animals robustly activates quiescent olfactory neural stem cells
por: Brann, Jessica H., et al.
Publicado: (2015)

Molecular Signatures of Quiescent, Mobilized and Leukemia-Initiating Hematopoietic Stem Cells
por: Forsberg, E. Camilla, et al.
Publicado: (2010)

Trehalose ameliorates peritoneal fibrosis by promoting Snail degradation and inhibiting mesothelial-to-mesenchymal transition in mesothelial cells
por: Miyake, Taito, et al.
Publicado: (2020)

Macrophages Promote Ovarian Cancer-Mesothelial Cell Adhesion by Upregulation of ITGA2 and VEGFC in Mesothelial Cells
por: Cho, Seung-Kye, et al.
Publicado: (2023)

Effect upon mitogenic stimulation of calcium-dependent phosphorylation of cytoskeleton-associated 350,000- and 80,000-mol-wt polypeptides in quiescent 3Y1 cells
Publicado: (1985)

Visceral and subcutaneous fat have different origins and evidence supports a mesothelial source
por: Chau, You-Ying, et al.
Publicado: (2014)

Ventricular Tachycardia Caused by Mesothelial Cyst
por: Amirahmadi, Ali, et al.
Publicado: (2013)

Mesothelial cells in tissue repair and fibrosis
por: Mutsaers, Steven E., et al.
Publicado: (2015)

Mesothelial cyst of the round ligament of the liver
por: Carboni, Fabio, et al.
Publicado: (2016)

The panorama of different faces of mesothelial cells
por: Shidham, Vinod B.
Publicado: (2021)

Cytomorphology of nodular histiocytic/mesothelial hyperplasia
por: Jin, Xiaobing, et al.
Publicado: (2022)

Differentiated cytoplasmic granule formation in quiescent and non-quiescent cells upon chronological aging
por: Lee, Hsin-Yi, et al.
Publicado: (2016)

The WT1-like transcription factor Klumpfuss maintains lineage commitment of enterocyte progenitors in the Drosophila intestine
por: Korzelius, Jerome, et al.
Publicado: (2019)

Planar Polarization in Embryonic Epidermis Orchestrates Global Asymmetric Morphogenesis of Hair Follicles
por: Devenport, Danelle, et al.
Publicado: (2008)

Macrophage derived Wnt signalling opposes Notch signalling in a Numb mediated manner to specify HPC fate in chronic liver disease in human and mouse
por: Boulter, Luke, et al.
Publicado: (2012)

Exosome‐Based Mitochondrial Delivery of circRNA mSCAR Alleviates Sepsis by Orchestrating Macrophage Activation
por: Fan, Li, et al.
Publicado: (2023)

Restricted differentiative capacity of Wt1-expressing peritoneal mesothelium in postnatal and adult mice
por: Wilm, Thomas P., et al.
Publicado: (2021)

Developmental patterns and characteristics of epicardial cell markers Tbx18 and Wt1 in murine embryonic heart
por: Zeng, Bin, et al.
Publicado: (2011)

Toll-like receptor 2 orchestrates a tumor suppressor response in non-small cell lung cancer
por: Millar, Fraser R., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_55io4asjtntcr4jtt46g04fe6v