A spatial similarity of stereochemical environments formed by amino acid residues defines a common epitope of two non-homologous proteins

It is critical for development of high-quality antibodies in research and diagnostics to predict accurately their cross-reactivities with “off-target” molecules, which potentially induce false results. Herein, we report a good example of such a cross-reactivity for an off-target due to a stereochemi...

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Detalles Bibliográficos
Autores principales: Nakashima, Kentaro, Iwashita, Shintaro, Suzuki, Takehiro, Kato, Chieko, Kohno, Toshiyuki, Kamei, Yasutomi, Sasaki, Motoki, Urayama, Osamu, Ohno-Iwashita, Yoshiko, Dohmae, Naoshi, Song, Si-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794283/
https://www.ncbi.nlm.nih.gov/pubmed/31616018
http://dx.doi.org/10.1038/s41598-019-51350-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794283/
https://www.ncbi.nlm.nih.gov/pubmed/31616018
http://dx.doi.org/10.1038/s41598-019-51350-2

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