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A spatial similarity of stereochemical environments formed by amino acid residues defines a common epitope of two non-homologous proteins
It is critical for development of high-quality antibodies in research and diagnostics to predict accurately their cross-reactivities with “off-target” molecules, which potentially induce false results. Herein, we report a good example of such a cross-reactivity for an off-target due to a stereochemi...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794283/ https://www.ncbi.nlm.nih.gov/pubmed/31616018 http://dx.doi.org/10.1038/s41598-019-51350-2 |