The TLR7/8 agonist R848 remodels tumor and host responses to promote survival in pancreatic cancer

A priority in cancer research is to innovate therapies that are not only effective against tumor progression but also address comorbidities such as cachexia that limit quality and quantity of life. We demonstrate that TLR7/8 agonist R848 induces anti-tumor responses and attenuates cachexia in murine...

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Detalles Bibliográficos
Autores principales: Michaelis, Katherine A., Norgard, Mason A., Zhu, Xinxia, Levasseur, Peter R., Sivagnanam, Shamilene, Liudahl, Shannon M., Burfeind, Kevin G., Olson, Brennan, Pelz, Katherine R., Angeles Ramos, Diana M., Maurer, H. Carlo, Olive, Kenneth P., Coussens, Lisa M., Morgan, Terry K., Marks, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794326/
https://www.ncbi.nlm.nih.gov/pubmed/31615993
http://dx.doi.org/10.1038/s41467-019-12657-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794326/
https://www.ncbi.nlm.nih.gov/pubmed/31615993
http://dx.doi.org/10.1038/s41467-019-12657-w

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