Environmental Electrophile-Mediated Toxicity in Mice Lacking Nrf2, CSE, or Both

BACKGROUND: Transcription factor Nrf2 (nuclear factor-erythroid 2-related factor 2) plays a key role in detoxification of electrophiles via formation of glutathione (GSH) adducts and subsequent excretion into extracellular spaces. We found that reactive sulfur species (RSS), such as cysteine persulf...

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Detalles Bibliográficos
Autores principales: Akiyama, Masahiro, Unoki, Takamitsu, Shinkai, Yasuhiro, Ishii, Isao, Ida, Tomoaki, Akaike, Takaaki, Yamamoto, Masayuki, Kumagai, Yoshito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794492/
https://www.ncbi.nlm.nih.gov/pubmed/31166132
http://dx.doi.org/10.1289/EHP4949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794492/
https://www.ncbi.nlm.nih.gov/pubmed/31166132
http://dx.doi.org/10.1289/EHP4949

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