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Synthesis and Enzymatic Incorporation of a Responsive Ribonucleoside Probe That Enables Quantitative Detection of Metallo-Base Pairs

[Image: see text] Synthesis of a highly responsive fluorescent ribonucleoside analogue based on a 5-methoxybenzofuran uracil core, enzymatic incorporation of its triphosphate substrate into RNA transcripts, and its utility in the specific detection and estimation of Hg(2+)-ion-mediated metallo-base...

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Detalles Bibliográficos
Autores principales: Manna, Sudeshna, Srivatsan, Seergazhi G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794643/
https://www.ncbi.nlm.nih.gov/pubmed/31184159
http://dx.doi.org/10.1021/acs.orglett.9b01544